Cardiac Resynchronization Therapy for the Treatment of Heart Failure

Please note: All assessments are current as of the review date; however, new evidence that may have been published subsequently is not considered.
Review Date: October 20, 2004
Recommendation: This topic was reviewed by the California Technology Assessment Forum on October 20, 2004. It was determined that:
  • The implantation of biventricular pacemakers for patients with a prolonged QRS interval and Class III or IV heart failure meets CTAF criteria for treatment of congestive heart failure in patients who fulfill all of the following criteria:
    NYHA Class III or IV
    Left ventricular ejection fraction ≤35%
    QRS duration of ≥120msec
    Stable pharmacological medical regimen prior to implant. Including (or having failed) an ACE inhibitor (or an angiotensin receptor blocker), a beta-blocker, spironolactone, digoxin, and loop diuretics
  • The implantation of a dual function device (CRT+ICD) for patients with an indication for an ICD, a prolonged QRS interval and Class III or IV meets CTAF criteria. Patients must fulfill all of the criteria noted for implantation of biventricular pacemakers above including having an indication for an ICD.
Decision: Does Meet CTAF Criteria
Full Assessment: Download (PDF)

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